Neglected but deadly- the global failure to confront neurological diseases affecting billions

By Life In Humanity Analysis Desk

Neurological disorders and the nervous system are areas that have to be handled with optimal care, seen the mammoth importance of the nervous system. Credit: Cleveland Clinic.

Neurological diseases constitute a severe problem which is battering the world. A staggeringly huge number of people are suffering from these diseases, while a big number is also deceasing every year as a result of these conditions- several of which are preventable. The World Economic Forum [WEF], with its 18 December 2025 story entitled “The top global health stories from 2025” updated on 13 January 2026, explains “Breakthroughs in Brain Health.

Neurological conditions affect more than 40% of the global population, which is around 3 billion people, a WHO [World Health Organization] report found in October. Stroke, migraine, meningitis, Alzheimer’s and other dementias are a few examples of the types of neurological disorders that are responsible for over 11 million deaths globally each year. Despite this, fewer than one in three countries around the world has a national policy to address this issue.”  

The forum cites Dr. Jeremy Farrar, WHO Assistant Director-General, as saying “Many of these neurological conditions can be prevented or effectively treated, yet services remain out of reach for most – especially in rural and underserved areas – where people too often face stigma, social exclusion and financial hardship.”

Complexity and expanding burden of neurological conditions

Neurological conditions are any disorders or diseases which attack the brain, spinal cord and/or nerves. Think of the spinal cord as a main highway of information connecting your brain to your body—without it, movement and sensation would not operate properly. “Because these systems control your mind and body, neurological conditions can affect the way you think and feel and interact with the world. Neurological conditions can affect anyone at any age.

Neurological conditions can be caused by a variety of factors, including genes, the environment, bacterial or viral infections and traumatic injuries or accidents. It’s not always possible to tell what causes a neurological condition, although research is ongoing,” points out the Neurological Alliance, coalition of over 90 organizations working together to improve services for 1 in 6 people in the UK who live with a neurological condition and their families and loved ones.

There exist not less than 600 neurological diseases. Image taken from Nanavati Max Super Specialty Hospital.

WEF states “One of the most common neurological conditions is dementia, and of the 57 million people living with the condition worldwide, 60-70% are thought to have Alzheimer’s disease. With the number of people with dementia expected to increase to 152 million by 2050, the pressure is on to find a solution to this debilitating and devastating disease. The most common form of dementia, Alzheimer’s, is a brain disorder characterized by the slow erosion of a person’s memory and thinking skills.” According to the WHO, over 60% of these 57 million people live in low-and middle-income countries. It adds “Every year, there are nearly 10 million new cases.

There exist so numerous other neurological conditions. The alliance says “There are over 600 known neurological conditions and this number is increasing all the time as diagnosis improves. Doctors, researchers and clinicians sometimes find it helpful to group neurological conditions together in four main categories:

Sudden onset conditions like stroke, traumatic brain injury, spinal injury, meningitis or Guillain-Barre Syndrome. Intermittent conditions, like epilepsy, migraine or cavernoma. Progressive conditions, like Parkinson’s disease. Stable with changing needs, like Tourette’s syndrome, and cerebral palsy.”

Further details on the diseases mentioned by the alliance

A stroke is a medical emergency happening when blood flow to part of the brain is interrupted or a blood vessel bursts, robbing brain tissue of oxygen and causing cell death. It can beget lasting brain damage, disability, or death if not instantly treated.

A traumatic brain injury means damage to the brain caused by an outside force. For example, a forceful blow or bump on the head can cause it.

A spinal cord injury involves damage to any part of the spinal cord, according to Mayo Clinic- one of the most prestigious hospitals in the world. “It also can include damage to nerves at the end of the spinal cord, known as the cauda equina. The spinal cord sends and receives signals between the brain and the rest of the body. A spinal cord injury often causes permanent changes in strength, feeling and other body functions below the site of the injury. People who have had a spinal cord injury also may experience mental, emotional and social side effects.

Brain health has to be assured to the maximal extent. Pixabay/Holdendrils.

Meningitis is an infection attacking protective membranes which encircle the brain and spinal cord (meninges). It can occur to anyone, but stands most common among babies, young children, teenagers and young adults. Meningitis can become very serious, if it is not rapidly cured.

Guillain-Barre Syndrome represents a rare neurological disorder where the body’s immune system mistakenly attacks the peripheral nerves-the nerves outside the brain and spinal cord. This signifies that the body’s defense system turns against its own nerves. It can cause weakness, numbness or paralysis. “Weakness and tingling in the hands and feet are usually the first symptoms. These sensations can quickly spread and may lead to paralysis. In its most serious form, Guillain-Barre syndrome is a medical emergency. Most people with the condition need treatment in a hospital,” says Mayo Clinic.

Guillain-Barre syndrome is rare, and the exact cause is not known. There’s no known cure for Guillain-Barre syndrome. Several treatment options can ease symptoms and help speed recovery. Most people recover completely from Guillain-Barre syndrome, but some serious illnesses can be fatal. While recovery may take up to several years, most people are able to walk again six months after symptoms first began. Some people may have lasting effects, such as weakness, numbness or fatigue.”

Mayo Clinic explains that epilepsy constitutes a brain disease which causes recurring seizures. A seizure means a very sudden attack of an illness in which a person gets unconscious or develops violent movements. “There are many types of epilepsy. In some people, the cause can be found. In others, the cause is not known. Epilepsy also is known as a seizure disorder.

Epilepsy is common and affects people of all genders, races, ethnic backgrounds and ages. Having a single seizure doesn’t mean you have epilepsy. Epilepsy is diagnosed if you’ve had at least two seizures without a clear cause at least 24 hours apart.” Epilepsy can cause a person to fall to the ground.

Migraine is a type of neurological condition characterized by recurrent, often intense headaches, usually affecting one side of the head. It is often accompanied by nausea and disturbed vision.

Our brains are paramount to human life and functioning. Our brains are of supreme importance, since they govern everything we do. So, let’s jealously maintain them. Picture from Pixabay/ The Digital Artist.

A cavernoma is a cluster of abnormal blood vessels in the brain or spinal cord that can sometimes leak blood and cause problems. A cavernoma consists of abnormally thin and fragile blood vessel walls. Unlike normal blood vessels, these walls are weak and not well structured. Compare it to a worn-out pipe with thin walls—instead of holding water properly, it can drip or burst, letting fluid escape where it shouldn’t. A blood vessel wall is the thin layer of tissue that surrounds and supports a blood vessel, helping it to hold blood and control its flow.

Parkinson’s disease is a progressive neurological disorder that affects movement, caused by the gradual loss of brain cells that produce dopamine- a chemical needed to control body movements. “Parkinson’s disease affects walking, balance and coordination, leading to shuffling, smaller steps, slower pace, reduced arm swing and difficulty turning,” says Parkinson’s Foundation in its dateless piece “Trouble Moving or Walking”.

Tourette syndrome is a neurological condition characterized by repetitive, involuntary movements and sounds called tics. In simpler terms, it forms a disorder when a person produces sudden, uncontrollable movements or noises that they cannot easily stop. For instance, a person may suddenly blink their eyes repeatedly or jerk their head to the side without intending to do so. A person may produce a short sound like throat clearing or a grunt that comes out involuntarily and is hard to suppress. Throat clearing means the act of forcing air out of the throat to remove irritation or mucus so you can speak more clearly.

Cerebral palsy is a group of neurological disorders that affect movement, muscle tone, and posture, engendered by damage to the developing brain, usually before, during, or shortly after birth. These disorders, for example, cause (1) muscle stiffness or weakness that limits movement — for example, difficulty gripping objects, bending joints, or controlling limbs, and (2) impaired balance and coordination — for instance, unsteady walking, frequent falls, or difficulty standing or performing precise actions like writing. Bending joints refers to moving the joints of the arms and legs, such as the elbows, knees, wrists, and ankles. Controlling limbs means being able to move and coordinate the arms and legs in a deliberate and controlled way.

More about dementia

Types of dementia, according to this illustration, include frontotemporal dementia, Lewy body dementia, vascular dementia, Alzheimer’s disease, mixed dementia, and Huntington’s disease.

Dementia’ does not constitute a single disease; but instead, it refers to an umbrella term for a group of disorders or conditions that progressively impair brain function. In its 31 March 2025 account headlined “Dementia”, the World Health Organization [WHO] reports “Dementia is a term for several diseases that affect memory, thinking, and the ability to perform daily activities. The illness gets worse over time. It mainly affects older people but not all people will get it as they age.

The WHO adds that factors which heighten the risk of contracting dementia include age (more common in those 65 or older), high blood pressure (hypertension), high blood sugar (diabetes), being overweight or obese, smoking, drinking too much alcohol, being physically inactive, and being socially isolated. Dementia is a syndrome that can be caused by a number of diseases which over time destroy nerve cells and damage the brain, typically leading to deterioration in cognitive function (i.e. the ability to process thought) beyond what might be expected from the usual consequences of biological ageing,” says the WHO.

This UN agency in charge of health across the world adds “While consciousness is not affected, the impairment in cognitive function is commonly accompanied, and occasionally preceded, by changes in mood, emotional control, behaviour, or motivation. Dementia has physical, psychological, social and economic impacts, not only for people living with dementia, but also for their carers, families and society at large. There is often a lack of awareness and understanding of dementia, resulting in stigmatization and barriers to diagnosis and care.”

According to the WHO, dementia forms economic toll. “In 2019, dementia cost economies globally US$ 1.3 trillion, approximately 50% of these costs are attributable to care provided by informal carers (e.g. family members and close friends), who provide on average 5 hours of care and supervision per day,” explains the WHO before adding “Dementia results from a variety of diseases and injuries that affect the brain. Dementia is currently the seventh leading cause of death and one of the major causes of disability and dependency among older people globally.

The organization points out that women are extremely touched. “Women are disproportionately affected by dementia, both directly and indirectly. Women experience higher disability-adjusted life years and mortality due to dementia, but also provide 70% of care hours for people living with dementia.” The phrase ‘Women experience higher disability-adjusted life years (DALYs) and mortality’ means that women lose more years of healthy life—either by living longer with disability or by dying earlier from the condition—compared to men.

According to the WHO, early signs and symptoms include forgetting things or recent events, losing or misplacing things, getting lost when walking or driving, being confused even in familiar places, losing track of time, difficulties solving problems or making decisions, problems following conversations or trouble finding words, difficulties performing familiar tasks and misjudging distances to objects visually. “Symptoms get worse over time. Eventually, most people with dementia will need others to help with daily activities.”

Brain health is central to overall well-being and the ability to think, feel, and function effectively. Credit: Pixabay/Geralt.

Common changes in mood and behavior involve feeling anxious, sad, or angry about memory loss; personality changes; inappropriate behavior; withdrawal from work or social activities; and being less interested in other people’s emotions. The WHO explains “Changes in mood and behaviour sometimes happen even before memory problems occur. Dementia affects each person in a different way, depending upon the underlying causes, other health conditions and the person’s cognitive functioning before becoming ill.

Most symptoms become worse over time, while others might disappear or only occur in the later stages of dementia. As the disease progresses, the need for help with personal care increases. People with dementia may not be able to recognize family members or friends, develop difficulties moving around, lose control over their bladder and bowels, have trouble eating and drinking and experience behaviour changes such as aggression that are distressing to the person with dementia as well as those around them.”

Treatment and preclusion neurological diseases

The WHO states “There is no cure for dementia, but a lot can be done to support both people living with the illness and those who care for them. People with dementia can take steps to maintain their quality of life and promote their well-being by being physically active [and] taking part in activities and social interactions that stimulate the brain and maintain daily function.

This organization says that there exist medications which can be employed to address dementia symptoms. “If people living with dementia are at risk of hurting themselves or others, medicines like haloperidol and risperidone can help, but these should never be used as the first treatment.”

To maintain your brain health, Mayo Clinic, in its 29December 2022 piece titled “6 tips to keep your brain healthy” recommends exercising regularly, plenty of sleep, a Mediterranean diet, constant mental activity, involvement in social interactions, and ensuring health for blood vessels.

This hospital says “Exercise regularly. Exercise has many known benefits, and regular physical activity also benefits the brain. Multiple research studies show that physical active people are less likely to experience a decline in their mental function and have a lower risk of developing Alzheimer’s disease. These benefits result from increased blood flow to your brain during exercise. It also tends to counter some of the natural reduction in brain connections that occur during aging, reversing some of the problems. Aim to exercise several times per week for 30 to 60 minutes. You can walk, swim, play tennis or do any other moderate aerobic activity that increases your heart rate.”

Quality sleep is essential for maintaining brain health and optimal daily human functioning. Image from Pixabay/MIssKarin.

Mayo Clinic says that sleep fulfills an important role in your brain health, some theories stating that sleep helps to clear abnormal proteins in your brain and consolidates memories, “which boosts your overall memory and brain health. Aim for seven to eight consecutive hours of sleep per night, not fragmented sleep of two- or three-hour increments. Consecutive sleep gives your brain the time to consolidate and store your memories effectively. 

Sleep apnea harms your brain’s health and could be why you may struggle to get consecutive hours of sleep. Talk with your health care team if you or a loved one suspects you have sleep apnea.” Sleep apnea is a sleep disorder in which a person repeatedly stops and starts breathing while asleep. These pauses in breathing can last for a few seconds to over a minute and may happen many times during the night, often without the person realizing it.

Your diet plays a large role in your brain health, according to Mayo Clinic which advises “Consider following a Mediterranean diet, which emphasizes plant-based foods, whole grains, fish and healthy fats, such as olive oil.” “It incorporates less red meat and salt than a typical American diet. Studies show people who closely follow a Mediterranean diet are less likely to have Alzheimer’s disease than people who don’t follow the diet.”

The hospital however highlights that further research is needed to identify parts of the diet which help brain to work the most. It adds “However, we know that omega fatty acids found in extra-virgin olive oil and other healthy fats are vital for your cells to function correctly, appear to decrease your risk of coronary artery disease, increase mental focus and slow cognitive decline in older adults.”

Mayo Clinic says that your brain acts like a muscle so that you need to “use it or lose it. Stay mentally active. There are many things that you can do to keep your brain in shape, such as doing crossword puzzles or Sudoku, reading, playing cards or putting together a jigsaw puzzle. Consider it cross-training your brain. Incorporate different types of activities to increase the effectiveness.

Most health care teams don’t recommend the paid brain-training programs available. These programs often overpromise results or focus on memorization skills that aren’t useful in everyday life. Your brain can get just as good of a workout through reading or challenging yourself with puzzles. Finally, don’t watch too much TV, as that is a passive activity and does little to stimulate your brain.”

Socializing, too, is key for health. Imagine if you were always delighted like this; it would accomplish wonders. Image sourced from Pixabay/iStockphoto.

This hospital eventually says “Remain socially involved. Social interaction helps ward off depression and stress, which can contribute to memory loss. Look for opportunities to connect with loved ones, friends and others, especially if you live alone. Research links solitary confinement to brain atrophy, so remaining socially active may have the opposite effect and strengthen the health of your brain.

Keep your blood vessels healthy. The health of your arteries and veins is important to your heart health but it is also critical for brain health. Get your blood pressure, blood sugar and cholesterol checked regularly and take steps to keep your numbers within a normal range.

Dr. Raveesh Sunkara, with his 22 May 2025 story headlined “Top 10 Effective Ways to Prevent Neurological Problems & Brain Disorders”, also says “Get quality sleep. Sleep rejuvenates your brain. Without it, you can develop neurological symptoms such as confusion, poor concentration, and loss of memory. Tips to sleep better: avoid screens at night [,] fixed sleeping schedule [, and] reduce caffeine and sugar at night.

Manage stress actively. Long-term stress causes neurological symptoms such as anxiety and memory loss. Stress is an underlying reason for neurological diseases such as migraines and insomnia.  Protect your head. Injuries are a leading cause of neurological disorders treatment later in life. Safety tips: always wear a helmet when cycling [,] wear seat belts in vehicles [, and] avoid dangerous sports without protective gear. Head injuries tend to have symptoms of long-term neuro problems.

Dr. Sunkara admonishes you to consult a doctor instantaneously after you develop a neurological disorder. “Early diagnosis and expert consultation. If you experience memory problems, sudden confusion, or loss of coordination, don’t disregard them. They are potential early symptoms of a neurological disorder. Approach a brain problem doctor urgently. Early diagnosis assists in quick recovery. When to see a neurologist? Here are the symptoms you can’t ignore: recurring headaches or migraines [,] walking or speech difficulties [,] confusion or memory loss [,] numbness or tingling in the hands/feet [and] vision loss suddenly. These could be neuro problems symptoms requiring neurological disorder treatment immediately.”

Dr. Sunkara defines a neurological problem as any abnormality affecting the nervous system. The nervous system transmits messages between the brain and the rest of the body. “Often, this starts with mild symptoms like headaches, memory loss, or confusion. What are the usual neurological symptoms? Numbness, balance difficulties, vision problems, memory loss, and speech problems are the usual neurological symptoms patients experience. How are neurological disorders treated? It depends, since treatment for neurological diseases varies widely based on the disease. Treatment may include medications, surgery, therapy, or lifestyle changes.”

Socializing does benefit our nervous systems, and quite significantly. Positive social interaction helps to regulate the nervous system by reducing stress and promoting a sense of safety and connection. When you engage with others, especially in supportive relationships, your body tends to lower stress hormones like cortisol and increase ‘feel-good’ chemicals such as oxytocin and serotonin. This supports both brain function and emotional stability.

On the other hand, social isolation can strain the nervous system, increasing anxiety, low mood, and even the risk of cognitive decline over time. So, regular, meaningful social interaction represents an important part of maintaining both brain health and overall nervous system balance.

Your nervous system amounts to a resource of unparalleled value which has to be maximally treasured. Cleveland Clinic explains it in these words “Your nervous system plays a role in everything you do. The three main parts of your nervous system are your brain, spinal cord and nerves. It helps you move, think and feel. It even regulates the things you do but don’t think about like digestion. It contains the central nervous system and the peripheral nervous system. Your nervous system is your body’s command center. It’s made up of your brain, spinal cord and nerves.

Your nervous system works by sending messages, or electrical signals, between your brain and all the other parts of your body. These signals tell you to breathe, move, speak and see, for example. Your nervous system keeps track of what’s going on inside and outside of your body and decides how to respond to any situation you’re in. Your nervous system regulates complicated processes like thoughts and memory. It also plays an essential role in the things your body does without thinking, like blushing, sweating and blinking.”

The sheer scale and severity of neurological disorders reveal a crisis that can no longer be ignored. When conditions affecting the very system that enables us to think, move, feel, and interact with the world are striking billions and claiming millions of lives each year, complacency becomes not just dangerous—but deadly. The nervous system is not merely another bodily system; it constitutes the body’s command center, governing every conscious and unconscious function that sustains human life. Any damage to it reverberates across the entire organism, often with irreversible consequences.

Therefore, neurological disorders must be approached with the highest level of urgency, care, and investment—from early detection and equitable access to treatment, to sustained research and public awareness. To neglect brain and nervous system health is to jeopardize the very essence of human functioning and dignity. Confronting this global burden is not optional; it amounts to an imperative that demands coordinated action, compassion, and unwavering commitment to protect one of the most vital systems that defines our existence.

 

Leave a Reply

Your email address will not be published. Required fields are marked *